The Effect of a High-Fat Diet and Grape Powder on the Abundance of Sulfidogenic Bacteria in the Colonic Digesta of C57BL/6J Mice

Abstract

Recently scientists have made and interesting link with colon cancer, diet and Bilophila wadsworthia. For 16 weeks 50 C57BL/6J mice were fed four different high-fat diets and one low-fat diet each containing certain percentages of grape powder. At the end of the 16 weeks, colonic digesta samples were taken from the mice in order to analyze how much bacteria existed in their colon at the end of the 16 weeks. The B. wadsworthia abundance was higher in the low-fat diet than the 3% and 5% grape powder diets, suggesting other microbial targets may be appropriate for analysis.